Mechanisms responsible for the effect of median nerve electrical stimulation on traumatic brain injury-induced coma: orexin-A-mediated N-methyl-D-aspartate receptor subunit NR1 upregulation

Mechanisms responsible for the effect of median nerve electrical stimulation on traumatic brain injury-induced coma: orexin-A-mediated N-methyl-D-aspartate receptor subunit NR1 upregulation

Electrical stimulation of the median nerve is a noninvasive technique that facilitates awakening from coma. In rats with traumatic brain injury-induced coma, median nerve stimulation markedly enhances prefrontal cortex expression of orexin-A and its receptor, orexin receptor 1. To further understand...

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Bibliographic Details
Main Authors: Zhen Feng, Qing Du
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; NR1; median nerve electrical stimulation; traumatic brain injury; coma; wakefulness; orexin-A; prefrontal cortex; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=6;spage=951;epage=956;aulast=Feng

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=6;spage=951;epage=956;aulast=Feng

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