miR-17-5p targets the p300/CBP-associated factor and modulates androgen receptor transcriptional activity in cultured prostate cancer cells

<p>Abstract</p> <p>Background</p> <p>Androgen receptor (AR) signalling is critical to the initiation and progression of prostate cancer (PCa). Transcriptional activity of AR involves chromatin recruitment of co-activators, including the p300/CBP-associated factor (PCAF)...

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Bibliographic Details
Main Authors: Gong Ai-Yu, Eischeid Alex N, Xiao Jing, Zhao Jian, Chen Dongqing, Wang Zhao-Yi, Young Charles YF, Chen Xian-Ming
Format: Article
Language:English
Published: BMC 2012-10-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/12/492