Analysis of serum Hsp90 as a potential biomarker of β cell autoimmunity in type 1 diabetes.

Analysis of serum Hsp90 as a potential biomarker of β cell autoimmunity in type 1 diabetes.

Heat shock protein 90 (Hsp90) is a protein chaperone that is upregulated and released from pancreatic β cells under pro-inflammatory conditions. We hypothesized that serum Hsp90 may have utility as a biomarker of type 1 diabetes risk and exhibit elevations before the onset of clinically significant...

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Bibliographic Details
Main Authors: Gail J Ocaña, Emily K Sims, Renecia A Watkins, Susanne Ragg, Kieren J Mather, Richard A Oram, Raghavendra G Mirmira, Linda A DiMeglio, Janice S Blum, Carmella Evans-Molina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0208456

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https://doi.org/10.1371/journal.pone.0208456

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