Pharmacokinetic Profiles of Active Ingredients and Its Metabolites Derived from Rikkunshito, a Ghrelin Enhancer, in Healthy Japanese Volunteers: A Cross-Over, Randomized Study.

Pharmacokinetic Profiles of Active Ingredients and Its Metabolites Derived from Rikkunshito, a Ghrelin Enhancer, in Healthy Japanese Volunteers: A Cross-Over, Randomized Study.

Rikkunshito, a traditional Japanese (Kampo) medicine, has been used to treat upper gastrointestinal disorders such as functional dyspepsia and gastroesophageal reflux. This study investigated the exposure and pharmacokinetics of the ingredients of rikkunshito in healthy volunteers.First, an explorat...

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Bibliographic Details
Main Authors: Hiroyuki Kitagawa, Masaya Munekage, Takashi Matsumoto, Chiharu Sadakane, Miwako Fukutake, Katsuyuki Aoki, Junko Watanabe, Kazuya Maemura, Tomohisa Hattori, Yosio Kase, Yasuhito Uezono, Akio Inui, Kazuhiro Hanazaki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4506051?pdf=render

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http://europepmc.org/articles/PMC4506051?pdf=render

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