Signatures of natural selection at the FTO (fat mass and obesity associated) locus in human populations.

Signatures of natural selection at the FTO (fat mass and obesity associated) locus in human populations.

Polymorphisms in the first intron of FTO have been robustly replicated for associations with obesity. In the Sorbs, a Slavic population resident in Germany, the strongest effect on body mass index (BMI) was found for a variant in the third intron of FTO (rs17818902). Since this may indicate populati...

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Bibliographic Details
Main Authors: Xuanshi Liu, Kerstin Weidle, Kristin Schröck, Anke Tönjes, Dorit Schleinitz, Jana Breitfeld, Michael Stumvoll, Yvonne Böttcher, Torsten Schöneberg, Peter Kovacs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4315420?pdf=render

Internet

http://europepmc.org/articles/PMC4315420?pdf=render

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