Predictive analysis methods for human microbiome data with application to Parkinson's disease.

Microbiome data consists of operational taxonomic unit (OTU) counts characterized by zero-inflation, over-dispersion, and grouping structure among samples. Currently, statistical testing methods are commonly performed to identify OTUs that are associated with a phenotype. The limitations of statisti...

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Bibliographic Details
Main Authors: Mei Dong, Longhai Li, Man Chen, Anthony Kusalik, Wei Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0237779