Alkaline phosphatase in pulmonary inflammation—a translational study in ventilated critically ill patients and rats

Alkaline phosphatase in pulmonary inflammation—a translational study in ventilated critically ill patients and rats

Abstract Background Alkaline phosphatase (AP), a dephosphorylating enzyme, is involved in various physiological processes and has been shown to have anti-inflammatory effects. Aim To determine the correlation between pulmonary AP activity and markers of inflammation in invasively ventilated critical...

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Bibliographic Details
Main Authors: Jenny Juschten, Sarah A. Ingelse, Lieuwe D. J. Bos, Armand R. J. Girbes, Nicole P. Juffermans, Tom van der Poll, Marcus J. Schultz, Pieter Roel Tuinman, for the BASIC study investigators
Format: Article
Language:English
Published: SpringerOpen 2020-12-01
Series:Intensive Care Medicine Experimental
Subjects:
Alkaline phosphatase
Acute lung injury
AP
ARDS
Pulmonary inflammation
Mechanical ventilation
Online Access:https://doi.org/10.1186/s40635-020-00335-x

Internet

https://doi.org/10.1186/s40635-020-00335-x

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