Notch activation is dispensable for D, L-sulforaphane-mediated inhibition of human prostate cancer cell migration.

D, L-Sulforaphane (SFN), a synthetic racemic analog of broccoli constituent L-sulforaphane, is a highly promising cancer chemopreventive agent with in vivo efficacy against chemically-induced as well as oncogene-driven cancer in preclinical rodent models. Cancer chemopreventive effect of SFN is char...

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Bibliographic Details
Main Authors: Eun-Ryeong Hahm, Kumar Chandra-Kuntal, Dhimant Desai, Shantu Amin, Shivendra V Singh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3436754?pdf=render