Fungal Symbionts Produce Prostaglandin E2 to Promote Their Intestinal Colonization

Fungal Symbionts Produce Prostaglandin E2 to Promote Their Intestinal Colonization

Candida albicans is a ubiquitous fungal symbiont that resides on diverse human barrier surfaces. Both mammalian and fungal cells can convert arachidonic acid into the lipid mediator, prostaglandin E2 (PGE2), but the physiological significance of fungus-derived PGE2 remains elusive. Here we report th...

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Bibliographic Details
Main Authors: Tze Guan Tan, Ying Shiang Lim, Alrina Tan, Royston Leong, Norman Pavelka
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
prostaglandin E2
Candida albicans
symbiont
host-microbe interactions
phagocyte
virulence
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00359/full

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https://www.frontiersin.org/article/10.3389/fcimb.2019.00359/full

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