IL-17 deficiency aggravates the streptozotocin‐induced diabetic nephropathy through the reduction of autophagosome formation in mice

Abstract Background Diabetic nephropathy (DN) is one of the most important medical complications of diabetes mellitus. Autophagy is an important mediator of pathological response and plays a critical role in inflammation during the progression of diabetic nephropathy. Interleukin (IL)-17A favorably...

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Bibliographic Details
Main Authors: Kyung-Hyun Kim, Geum-Lan Hong, Da-Young Jung, Shanika Karunasagara, Won-Il Jeong, Ju-Young Jung
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Molecular Medicine
Subjects:
Online Access:https://doi.org/10.1186/s10020-021-00285-4