Pancreatic Islet Protein Complexes and Their Dysregulation in Type 2 Diabetes

Pancreatic Islet Protein Complexes and Their Dysregulation in Type 2 Diabetes

Type 2 diabetes (T2D) is a complex disease that involves multiple genes. Numerous risk loci have already been associated with T2D, although many susceptibility genes remain to be identified given heritability estimates. Systems biology approaches hold potential for discovering novel T2D genes by con...

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Bibliographic Details
Main Authors: Søren Brunak, Helle Krogh Pedersen, Valborg Gudmundsdottir
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Genetics
Subjects:
diabetes
data integration
protein complexes
tissue specificity
pancreatic islets
patient network biology
Online Access:http://journal.frontiersin.org/article/10.3389/fgene.2017.00043/full

Internet

http://journal.frontiersin.org/article/10.3389/fgene.2017.00043/full

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