Anti-Cancer Activities of Thyrointegrin α<sub>v</sub>β<sub>3</sub> Antagonist Mono- and Bis-Triazole Tetraiodothyroacetic Acid Conjugated via Polyethylene Glycols in Glioblastoma

Integrin αvβ3 receptors are overexpressed in different tumors and their associated neovascularization and hence, represent a potential cancer target. We previously synthesized a high affinity thyrointegrin αvβ3, P<sub>4000</sub>-bi-TAT (tetrac derivative), with potent anticancer properti...

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Bibliographic Details
Main Authors: Kavitha Godugu, Mehdi Rajabi, Shaker A. Mousa
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
PEG
Online Access:https://www.mdpi.com/2072-6694/13/11/2780