Diffused Intra-Oocyte Hydrogen Peroxide Activates Myeloperoxidase and Deteriorates Oocyte Quality.

Hydrogen peroxide (H2O2) is a relatively long-lived signaling molecule that plays an essential role in oocyte maturation, implantation, as well as early embryonic development. Exposure to relatively high levels of H2O2 functions efficiently to accelerate oocyte aging and deteriorate oocyte quality....

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Bibliographic Details
Main Authors: Sana N Khan, Faten Shaeib, Tohid Najafi, Mahendra Kavdia, Bernard Gonik, Ghassan M Saed, Pravin T Goud, Husam M Abu-Soud
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4511228?pdf=render