Aspartic protease activities of schistosomes cleave mammalian hemoglobins in a host-specific manner

Aspartic protease activities of schistosomes cleave mammalian hemoglobins in a host-specific manner

We examined the efficiency of digestion of hemoglobin from four mammalian species, human, cow, sheep, and horse by acidic extracts of mixed sex adults of Schistosoma japonicum and S. mansoni. Activity ascribable to aspartic protease(s) from S. japonicum and S. mansoni cleaved human hemoglobin. In ad...

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Bibliographic Details
Main Authors: Jeffrey W Koehler, Maria E Morales, Bryan D Shelby, Paul J Brindley
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2007-02-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
schistosome
hemoglobin
aspartic protease
cathepsin D
host specificity
host range
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000100014&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000100014&lng=en&tlng=en

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