Analysis of the transcriptomic features of microsatellite instability subtype colon cancer

Analysis of the transcriptomic features of microsatellite instability subtype colon cancer

Abstract Background Programmed cell death protein 1(PD-1) blocking antibodies have been used to enhance immunity in solid tumors and achieve durable clinical responses with an acceptable safety profile in multiple types of cancer. However, only a subset of patients could benefit from PD-1 blockade t...

Full description

Bibliographic Details
Main Authors: Haiwei Wang, Xinrui Wang, Liangpu Xu, Ji Zhang, Hua Cao
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Cancer
Subjects:
PD-1
IFN-γ
MSI
Wnt-β-catenin signaling pathway
TGFβ signaling pathway
M1 macrophage cells
Online Access:http://link.springer.com/article/10.1186/s12885-019-5802-2

Internet

http://link.springer.com/article/10.1186/s12885-019-5802-2

Similar Items