Lynch syndrome-associated lung cancer: pitfalls of an immunotherapy-based treatment strategy in an unusual tumor type

Lynch syndrome-associated lung cancer: pitfalls of an immunotherapy-based treatment strategy in an unusual tumor type

Lynch syndrome is a hereditary cancer predisposition syndrome caused by germline alterations in mismatch repair (MMR) genes leading to increased risk of colon cancer as well as other cancer types. Non-small cell lung cancer (NSCLC) is not among typical Lynch syndrome-associated tumors: pembrolizumab...

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Bibliographic Details
Main Authors: Elena Maccaroni, Edoardo Lenci, Veronica Agostinelli, Valeria Cognigni, Riccardo Giampieri, Paola Mazzanti, Marzia Di Pietro Paolo, Francesca Bianchi, Cristiana Brugiati, Laura Belvederesi, Silvia Pagliaretta, Alessandra Mandolesi, Marina Scarpelli, Alberto Murrone, Francesca Morgese, Zelmira Ballatore, Rossana Berardi
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2021-06-01
Series:Exploration of Targeted Anti-tumor Therapy
Subjects:
lynch syndrome
immunotherapy
non-small cell lung cancer
microsatellite instability-high
pembrolizumab
Online Access:https://www.explorationpub.com/Journals/etat/Article/100244

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https://www.explorationpub.com/Journals/etat/Article/100244

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