Petunidin, a B-ring 5′-<i>O</i>-Methylated Derivative of Delphinidin, Stimulates Osteoblastogenesis and Reduces sRANKL-Induced Bone Loss

Petunidin, a B-ring 5′-<i>O</i>-Methylated Derivative of Delphinidin, Stimulates Osteoblastogenesis and Reduces sRANKL-Induced Bone Loss

Several lines of evidence suggest that oxidative stress is one of the key pathogenic mechanisms of osteoporosis. We aimed to elucidate the bone protective effects of petunidin, one of the most common anthocyanidins, considering its potent antioxidative activity. Petunidin (&gt;5 &#956;g/mL)...

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Bibliographic Details
Main Authors: Masahiro Nagaoka, Toyonobu Maeda, Sawako Moriwaki, Atsushi Nomura, Yasumasa Kato, Shumpei Niida, Marlena C. Kruger, Keiko Suzuki
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:International Journal of Molecular Sciences
Subjects:
petunidin
osteoblast
osteoclast
osteoporosis
anthocyanin
bone anabolism
Online Access:https://www.mdpi.com/1422-0067/20/11/2795

Internet

https://www.mdpi.com/1422-0067/20/11/2795

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