The First Contact of Human Dendritic Cells With Trypanosoma cruzi Reveals Response to Virus as an Unexplored Central Pathway

The First Contact of Human Dendritic Cells With Trypanosoma cruzi Reveals Response to Virus as an Unexplored Central Pathway

Chagas disease is a debilitating and neglected disease caused by the protozoan Trypanosoma cruzi. Soon after infection, interactions among T. cruzi and host innate immunity cells can drive/contribute to disease outcome. Dendritic cells (DCs), present in all tissues, are one of the first immune cells...

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Bibliographic Details
Main Authors: Natalia Gil-Jaramillo, Amanda Pereira Rocha, Tainá Raiol, Flávia Nader Motta, Cecília Favali, Marcelo M. Brigido, Izabela M. D. Bastos, Jaime M. Santana
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
Chagas disease
inflammasome
metacyclic trypomastigotes
transcriptome
virus infection
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.638020/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.638020/full

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