Biomechanical Conditioning Enhanced Matrix Synthesis in Nucleus Pulposus Cells Cultured in Agarose Constructs with TGFβ
Biomechanical signals play an important role in normal disc metabolism and pathology. For instance, nucleus pulposus (NP) cells will regulate metabolic activities and maintain a balance between the anabolic and catabolic cascades. The former involves factors such as transforming growth factor-β (TGF...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2012-01-01
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Series: | Journal of Functional Biomaterials |
Subjects: | |
Online Access: | http://www.mdpi.com/2079-4983/3/1/23/ |