The Genetic Architecture of Quantitative Traits Cannot Be Inferred from Variance Component Analysis.

Classical quantitative genetic analyses estimate additive and non-additive genetic and environmental components of variance from phenotypes of related individuals without knowing the identities of quantitative trait loci (QTLs). Many studies have found a large proportion of quantitative trait variat...

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Bibliographic Details
Main Authors: Wen Huang, Trudy F C Mackay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5094750?pdf=render