Defining epitope coverage requirements for T cell-based HIV vaccines: Theoretical considerations and practical applications

<p>Abstract</p> <p>Background</p> <p>HIV vaccine development must address the genetic diversity and plasticity of the virus that permits the presentation of diverse genetic forms to the immune system and subsequent escape from immune pressure. Assessment of potential HI...

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Bibliographic Details
Main Authors: Currier Jeffrey R, Robb Merlin L, Michael Nelson L, Marovich Mary A
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/9/1/212