The alveolar epithelial cells are involved in pulmonary vascular remodeling and constriction of hypoxic pulmonary hypertension

The alveolar epithelial cells are involved in pulmonary vascular remodeling and constriction of hypoxic pulmonary hypertension

Abstract Background Hypoxic pulmonary hypertension (HPH) is a common type of pulmonary hypertension and characterized by pulmonary vascular remodeling and constriction. Alveolar epithelial cells (AECs) primarily sense alveolar hypoxia, but the role of AECs in HPH remains unclear. In this study, we e...

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Bibliographic Details
Main Authors: Yanxia Wang, Xiaoming Li, Wen Niu, Jian Chen, Bo Zhang, Xiumin Zhang, Yingmei Wang, Shaokang Dang, Zhichao Li
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Respiratory Research
Subjects:
Alveolar epithelial cells
Hypoxic pulmonary hypertension
Pulmonary vascular remodeling and constriction
Reactive oxygen species
Online Access:https://doi.org/10.1186/s12931-021-01708-w

Internet

https://doi.org/10.1186/s12931-021-01708-w

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