Trypanosomatid RACK1 orthologs show functional differences associated with translation despite similar roles in Leishmania pathogenesis.

Trypanosomatid RACK1 orthologs show functional differences associated with translation despite similar roles in Leishmania pathogenesis.

RACK1 proteins belong to the eukaryote WD40-repeat protein family and function as spatial regulators of multiple cellular events, including signaling pathways, the cell cycle and translation. For this latter role, structural and genetic studies indicate that RACK1 associates with the ribosome throug...

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Bibliographic Details
Main Authors: Kohelia Choudhury, Daviel Cardenas, Ashok K Pullikuth, Andrew D Catling, Ashok Aiyar, Ben L Kelly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3108995?pdf=render

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http://europepmc.org/articles/PMC3108995?pdf=render

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