Argon Attenuates Multiorgan Failure in Relation with HMGB1 Inhibition

Argon Attenuates Multiorgan Failure in Relation with HMGB1 Inhibition

Argon inhalation attenuates multiorgan failure (MOF) after experimental ischemic injury. We hypothesized that this protection could involve decreased High Mobility Group Box 1 (HMGB1) systemic release. We investigated this issue in an animal model of MOF induced by aortic cross-clamping. Anesthetize...

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Bibliographic Details
Main Authors: Quentin de Roux, Fanny Lidouren, Agathe Kudela, Lina Slassi, Matthias Kohlhauer, Emilie Boissady, Matthieu Chalopin, Géraldine Farjot, Catherine Billoet, Patrick Bruneval, Bijan Ghaleh, Nicolas Mongardon, Renaud Tissier
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
argon
multiorgan failure
ischemia-reperfusion
inflammation
High Mobility Group Box 1 (HMGB1)
Online Access:https://www.mdpi.com/1422-0067/22/6/3257

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https://www.mdpi.com/1422-0067/22/6/3257

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