Normalization of B Cell Subsets but Not T Follicular Helper Phenotypes in Infants With Very Early Antiretroviral Treatment

Normalization of B Cell Subsets but Not T Follicular Helper Phenotypes in Infants With Very Early Antiretroviral Treatment

Introduction: Infant HIV-1-infection is associated with high morbidity and mortality if antiretroviral treatment (ART) is not initiated promptly. We characterized development of circulating T follicular helper cells (cTfh) and their relationship to naïve/memory B cell subsets in a cohort of neonates...

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Bibliographic Details
Main Authors: Sharon Shalekoff, Shayne Loubser, Bianca Da Costa Dias, Renate Strehlau, Stephanie Shiau, Shuang Wang, Yun He, Elaine J. Abrams, Louise Kuhn, Caroline T. Tiemessen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pediatrics
Subjects:
cTfh
B cells
infants
HIV-1
early antiretroviral therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2021.618191/full

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https://www.frontiersin.org/articles/10.3389/fped.2021.618191/full

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