Sox6 is necessary for efficient erythropoiesis in adult mice under physiological and anemia-induced stress conditions.

BACKGROUND: Definitive erythropoiesis is a vital process throughout life. Both its basal activity under physiological conditions and its increased activity under anemia-induced stress conditions are highly stimulated by the hormone erythropoietin. The transcription factor Sox6 was previously shown t...

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Bibliographic Details
Main Authors: Bogdan Dumitriu, Pallavi Bhattaram, Peter Dy, Yuanshuai Huang, Nayeem Quayum, Jan Jensen, Véronique Lefebvre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2918505?pdf=render