UCP2 inhibits ROS-mediated apoptosis in A549 under hypoxic conditions.

The Crosstalk between a tumor and its hypoxic microenvironment has become increasingly important. However, the exact role of UCP2 function in cancer cells under hypoxia remains unknown. In this study, UCP2 showed anti-apoptotic properties in A549 cells under hypoxic conditions. Over-expression of UC...

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Bibliographic Details
Main Authors: Sanming Deng, Ye Yang, Yong Han, Xiaofei Li, Xiaoping Wang, Xueyong Li, Zhipei Zhang, Yunjie Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3265501?pdf=render