Heritability and genetic associations of triglyceride and HDL-C levels using pedigree-based and empirical kinships

Abstract The heritability of a phenotype is an estimation of the percent of variance in that phenotype that is attributable to additive genetic factors. Heritability is optimally estimated in family-based sample populations. Traditionally, this involves use of a pedigree-based kinship coefficient ge...

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Bibliographic Details
Main Authors: Nicholas B. Blackburn, Arthur Porto, Juan M. Peralta, John Blangero
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Proceedings
Online Access:http://link.springer.com/article/10.1186/s12919-018-0133-x