Potential Antitumor Effects of 6-Gingerol in p53-Dependent Mitochondrial Apoptosis and Inhibition of Tumor Sphere Formation in Breast Cancer Cells

Potential Antitumor Effects of 6-Gingerol in p53-Dependent Mitochondrial Apoptosis and Inhibition of Tumor Sphere Formation in Breast Cancer Cells

Hormone-specific anticancer drugs for breast cancer treatment can cause serious side effects. Thus, treatment with natural compounds has been considered a better approach as this minimizes side effects and has multiple targets. 6-Gingerol is an active polyphenol in ginger with various modalities, in...

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Bibliographic Details
Main Authors: Nipin Sp, Dong Young Kang, Jin-Moo Lee, Se Won Bae, Kyoung-Jin Jang
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
6-Gingerol
DDR
G0/G1 arrest
mitochondrial apoptosis
tumorsphere
p53
Online Access:https://www.mdpi.com/1422-0067/22/9/4660

Internet

https://www.mdpi.com/1422-0067/22/9/4660

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