YAP and TAZ are transcriptional co-activators of AP-1 proteins and STAT3 during breast cellular transformation

The YAP and TAZ paralogs are transcriptional co-activators recruited to target sites by TEAD proteins. Here, we show that YAP and TAZ are also recruited by JUNB (a member of the AP-1 family) and STAT3, key transcription factors that mediate an epigenetic switch linking inflammation to cellular trans...

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Bibliographic Details
Main Authors: Lizhi He, Henry Pratt, Mingshi Gao, Fengxiang Wei, Zhiping Weng, Kevin Struhl
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-08-01
Series:eLife
Subjects:
YAP
TAZ
Online Access:https://elifesciences.org/articles/67312