Remdesivir Strongly Binds to RNA-Dependent RNA Polymerase, Membrane Protein, and Main Protease of SARS-CoV-2: Indication From Molecular Modeling and Simulations

Remdesivir Strongly Binds to RNA-Dependent RNA Polymerase, Membrane Protein, and Main Protease of SARS-CoV-2: Indication From Molecular Modeling and Simulations

Development of new drugs is a time-taking and expensive process. Comprehensive efforts are being made globally toward the search of therapeutics against SARS-CoV-2. Several drugs such as remdesivir, favipiravir, ritonavir, and lopinavir have been included in the treatment regimen and shown effective...

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Bibliographic Details
Main Authors: Faez Iqbal Khan, Tongzhou Kang, Haider Ali, Dakun Lai
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pharmacology
Subjects:
SARS-CoV-2
remdesivir
main protease
membrane proteins
RNA-dependent RNA polymerase
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.710778/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.710778/full

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