A systems biology analysis of the changes in gene expression via silencing of HPV-18 E1 expression in HeLa cells

Previous studies have reported the detection of a truncated E1 mRNA generated from HPV-18 in HeLa cells. Although it is unclear whether a truncated E1 protein could function as a replicative helicase for viral replication, it would still retain binding sites for potential interactions with different...

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Bibliographic Details
Main Authors: Andres Castillo, Lu Wang, Chihaya Koriyama, Yoshito Eizuru, King Jordan, Suminori Akiba
Format: Article
Language:English
Published: The Royal Society 2014-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.130119