The Role of DNA/Histone Modifying Enzymes and Chromatin Remodeling Complexes in Testicular Germ Cell Tumors

It is well established that cancer cells exhibit alterations in chromatin structure and accessibility. Indeed, the dysregulation of many protein-coding players with enzymatic activity (DNA and histone-modifying enzymes) and chromatin remodelers have been depicted in various tumor models in recent ye...

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Bibliographic Details
Main Authors: João Lobo, Rui Henrique, Carmen Jerónimo
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/1/6