Linear motif-mediated interactions have contributed to the evolution of modularity in complex protein interaction networks.

The modular architecture of protein-protein interaction (PPI) networks is evident in diverse species with a wide range of complexity. However, the molecular components that lead to the evolution of modularity in PPI networks have not been clearly identified. Here, we show that weak domain-linear mot...

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Bibliographic Details
Main Authors: Inhae Kim, Heetak Lee, Seong Kyu Han, Sanguk Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4191887?pdf=render