Increased glial glutamate transporter EAAT2 expression reduces epileptogenic processes following pilocarpine-induced status epilepticus
Several lines of evidence indicate that glutamate plays a crucial role in the initiation of seizures and their propagation; abnormal glutamate release causes synchronous firing of large populations of neurons, leading to seizures. In the present study, we investigated whether enhanced glutamate upta...
Main Authors: | Qiongman Kong, Kou Takahashi, Delanie Schulte, Nathan Stouffer, Yuchen Lin, Chien-Liang Glenn Lin |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-08-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996112001210 |
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