Recent advances in human iPSC-derived models of the blood–brain barrier

Abstract The blood–brain barrier (BBB) is a critical component of the central nervous system that protects neurons and other cells of the brain parenchyma from potentially harmful substances found in peripheral circulation. Gaining a thorough understanding of the development and function of the huma...

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Bibliographic Details
Main Authors: Michael J. Workman, Clive N. Svendsen
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12987-020-00191-7