Expression of Human Mutant Huntingtin Protein in Drosophila Hemocytes Impairs Immune Responses

The pathogenic effect of mutant HTT (mHTT) which causes Huntington disease (HD) are not restricted to nervous system. Such phenotypes include aberrant immune responses observed in the HD models. However, it is still unclear how this immune dysregulation influences the innate immune response against...

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Bibliographic Details
Main Authors: Yu-Hsien Lin, Houda Ouns Maaroufi, Emad Ibrahim, Lucie Kucerova, Michal Zurovec
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02405/full