FoxO1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase

FoxO1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase

Dopaminergic neurons are important for regulating energy homeostasis. Here, the authors show the transcription factor FoxO1 negatively regulates tyrosine hydroxylase expression in midbrain dopaminergic neurons, and plays an important role in regulation of glucose homeostasis, energy expenditure, and...

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Bibliographic Details
Main Authors: Khanh V. Doan, Ann W. Kinyua, Dong Joo Yang, Chang Mann Ko, Sang Hyun Moh, Ko Eun Shong, Hail Kim, Sang-Kyu Park, Dong-Hoon Kim, Inki Kim, Ji-Hye Paik, Ronald A. DePinho, Seul Gi Yoon, Il Yong Kim, Je Kyung Seong, Yun-Hee Choi, Ki Woo Kim
Format: Article
Language:English
Published: Nature Publishing Group 2016-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12733

Internet

https://doi.org/10.1038/ncomms12733

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