Evaluation of parameters affecting performance and reliability of machine learning-based antibiotic susceptibility testing from whole genome sequencing data.

Prediction of antibiotic resistance phenotypes from whole genome sequencing data by machine learning methods has been proposed as a promising platform for the development of sequence-based diagnostics. However, there has been no systematic evaluation of factors that may influence performance of such...

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Bibliographic Details
Main Authors: Allison L Hicks, Nicole Wheeler, Leonor Sánchez-Busó, Jennifer L Rakeman, Simon R Harris, Yonatan H Grad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-09-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007349