Computationally efficient permutation-based confidence interval estimation for tail-area FDR

Challenges of satisfying parametric assumptions in genomic settings with thousands or millions of tests have led investigators to combine powerful False Discovery Rate (FDR) approaches with computationally expensive but exact permutation testing. We describe a computationally efficient permutation-b...

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Bibliographic Details
Main Authors: Joshua eMillstein, Dmitri eVolfson
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00179/full