Investigation of Biophysical Migration Parameters for Normal Tissue and Metastatic Cancer Cells After Radiotherapy Treatment

Investigation of Biophysical Migration Parameters for Normal Tissue and Metastatic Cancer Cells After Radiotherapy Treatment

A large body of literature has demonstrated that the mechanical properties of microenvironment have a key role in regulating cancer cell adhesion, motility, and invasion. In this work, we have introduced two additional parameters, named cell trajectory extension and area traveled by cell, to describ...

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Bibliographic Details
Main Authors: Valeria Panzetta, Giuseppe La Verde, Mariagabriella Pugliese, Cecilia Arrichiello, Paolo Muto, Marco La Commara, Vittoria D'Avino, Paolo A. Netti, Sabato Fusco
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Physics
Subjects:
breast cancer
mechanobiology
cell motility analysis
extracellular matrix stiffness
radiotherapy
Online Access:https://www.frontiersin.org/article/10.3389/fphy.2020.575906/full

Internet

https://www.frontiersin.org/article/10.3389/fphy.2020.575906/full

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