RNAi Screen for NRF2 Inducers Identifies Targets That Rescue Primary Lung Epithelial Cells from Cigarette Smoke Induced Radical Stress.

Chronic Obstructive Pulmonary Disease (COPD) is a highly prevalent condition characterized by inflammation and progressive obstruction of the airways. At present, there is no treatment that suppresses the chronic inflammation of the disease, and COPD patients often succumb to the condition. Excessiv...

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Bibliographic Details
Main Authors: Frances-Rose Schumacher, Steffen Schubert, Michael Hannus, Birte Sönnichsen, Carina Ittrich, Stefan Kreideweiss, Thimo Kurz, Jörg F Rippmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5104413?pdf=render