An Atomic-Level Perspective of HMG-CoA-Reductase: The Target Enzyme to Treat Hypercholesterolemia

An Atomic-Level Perspective of HMG-CoA-Reductase: The Target Enzyme to Treat Hypercholesterolemia

This review provides an updated atomic-level perspective regarding the enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoAR), linking the more recent data on this enzyme with a structure/function interpretation. This enzyme catalyzes one of the most important steps in cholesterol biosynt...

Full description

Bibliographic Details
Main Authors: Diana S. Gesto, Carlos M. S. Pereira, Nuno M. F. S. Cerqueira, Sérgio F. Sousa
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Molecules
Subjects:
HMG-CoAR
structure
biochemistry
regulation
statins
dimerization inhibitors.
Online Access:https://www.mdpi.com/1420-3049/25/17/3891

Internet

https://www.mdpi.com/1420-3049/25/17/3891

Similar Items