Non-microRNA binding competitively inhibits LIN28 regulation

Non-microRNA binding competitively inhibits LIN28 regulation

Summary: RNA binding protein (RBP) expression is finite. For RBPs that are vastly outnumbered by their potential target sites, a simple competition for binding can set the magnitude of post-transcriptional control. Here, we show that LIN28, best known for its direct regulation of let-7 miRNA biogene...

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Bibliographic Details
Main Authors: Frederick E. Tan, Shashank Sathe, Emily C. Wheeler, Gene W. Yeo
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Cell Reports
Subjects:
RNA binding proteins
post-transcriptional regulation
microRNA
non-miRNA
ribosome occupancy
competitive inhibition
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721009475

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http://www.sciencedirect.com/science/article/pii/S2211124721009475

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