The tetraamine chelator outperforms HYNIC in a new technetium-99m-labelled somatostatin receptor 2 antagonist

Abstract Background Somatostatin receptor targeting radiopeptides are successfully being used to image, stage, and monitor patients with neuroendocrine tumours. They are exclusively agonists that internalise upon binding to the relevant receptor. According to recent reports, antagonists may be prefe...

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Bibliographic Details
Main Authors: Keelara Abiraj, Samer Ursillo, Maria Luisa Tamma, Svetlana N. Rylova, Beatrice Waser, Edwin C. Constable, Melpomeni Fani, Guillaume P. Nicolas, Jean Claude Reubi, Helmut R. Maecke
Format: Article
Language:English
Published: SpringerOpen 2018-08-01
Series:EJNMMI Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13550-018-0428-y