Insulin resistance enhances the mitogen-activated protein kinase signaling pathway in ovarian granulosa cells.

Insulin resistance enhances the mitogen-activated protein kinase signaling pathway in ovarian granulosa cells.

The ovary is the main regulator of female fertility. Granulosa cell dysfunction may be involved in various reproductive endocrine disorders. Here we investigated the effect of insulin resistance on the metabolism and function of ovarian granulosa cells, and dissected the functional status of the mit...

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Bibliographic Details
Main Authors: Linghui Kong, Qien Wang, Jiewen Jin, Zou Xiang, Taoyu Chen, Shanmei Shen, Hongwei Wang, Qian Gao, Yong Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5695281?pdf=render

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http://europepmc.org/articles/PMC5695281?pdf=render

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