Arthritis in Two Patients With Partial Recombination Activating Gene Deficiency

Arthritis in Two Patients With Partial Recombination Activating Gene Deficiency

Autoimmunity is becoming an increasingly recognized complication in patients with primary immunodeficiencies (PIDs), including a variety of combined immune deficiencies such as Recombination Activating Gene (RAG) defects. The approach to treating autoimmunity in PID patients is complex, requiring a...

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Bibliographic Details
Main Authors: Kevin Y. Wu, Pooja Purswani, Boglarka Ujhazi, Krisztian Csomos, Mihailova Snezhina, Naumova Elissaveta, Stefan Stefanov, Svetlana Sharapova, Maryssa Ellison, Diana Milojevic, Sinisa Savic, Ravishankar Sargur, Jolan E. Walter
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Pediatrics
Subjects:
recombination activating gene
RAG deficiency
rheumatoid arthritis
primary immunodeficiency
tocilizumab
refractory arthritis
Online Access:https://www.frontiersin.org/article/10.3389/fped.2019.00235/full

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https://www.frontiersin.org/article/10.3389/fped.2019.00235/full

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