New Perspectives on Roles of Alpha-Synuclein in Parkinson’s Disease

Parkinson’s disease (PD) is one of the synucleinopathies spectrum of disorders typified by the presence of intraneuronal protein inclusions. It is primarily composed of misfolded and aggregated forms of alpha-synuclein (α-syn), the toxicity of which has been attributed to the transition from an α-he...

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Bibliographic Details
Main Authors: Guoxin Zhang, Yun Xia, Fang Wan, Kai Ma, Xingfang Guo, Liang Kou, Sijia Yin, Chao Han, Ling Liu, Jinsha Huang, Nian Xiong, Tao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00370/full