Discovery and analysis of evolutionarily conserved intronic splicing regulatory elements.

Discovery and analysis of evolutionarily conserved intronic splicing regulatory elements.

Knowledge of the functional cis-regulatory elements that regulate constitutive and alternative pre-mRNA splicing is fundamental for biology and medicine. Here we undertook a genome-wide comparative genomics approach using available mammalian genomes to identify conserved intronic splicing regulatory...

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Bibliographic Details
Main Authors: Gene W Yeo, Eric L Van Nostrand, Tiffany Y Liang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1877881?pdf=render

Internet

http://europepmc.org/articles/PMC1877881?pdf=render

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