The 1ALCTL and 1BLCTL isoforms of Arg/Abl2 induce fibroblast activation and extra cellular matrix remodelling differently

The 1ALCTL and 1BLCTL isoforms of Arg/Abl2 induce fibroblast activation and extra cellular matrix remodelling differently

The fibrotic tissue and the stroma adjacent to cancer cells are characterised by the presence of activated fibroblasts (myofibroblasts) which play a role in creating a supportive tissue characterised by abundant extracellular matrix (ECM) secretion. The myofibroblasts remodel this tissue through sec...

Full description

Bibliographic Details
Main Authors: Barbara Torsello, Sofia De Marco, Silvia Bombelli, Elisa Chisci, Valeria Cassina, Roberta Corti, Davide Bernasconi, Roberto Giovannoni, Cristina Bianchi, Roberto A. Perego
Format: Article
Language:English
Published: The Company of Biologists 2019-03-01
Series:Biology Open
Subjects:
Arg
Abl2
Non-receptor tyrosine kinase
Fibroblast
Extra cellular matrix
Stroma remodelling
Online Access:http://bio.biologists.org/content/8/3/bio038554

Internet

http://bio.biologists.org/content/8/3/bio038554

Similar Items